Vetoryl (trilostane) is a medication used to treat Cushing's disease in dogs by reducing cortisol production. It helps manage symptoms and improve the overall well-being of affected pets.

Products with this symbol require a vet prescription in the checkout

Shop by

Prescription Brand
Product Type
View as Grid List

Showing 5 products

Set Descending Direction
per page
  1. You save 35%
    Vetoryl Capsules 60mg 3100
    Vetoryl® Hard Capsules for Dogs 60mg
    SRP £3.53
    Save £1.26
  2. You save 41%
    Vetoryl Capsules 120mg
    Vetoryl® Hard Capsules for Dogs 120mg
    SRP £6.10
    Save £2.55
  3. You save 37%
    Vetoryl Capsules 5mg 7780
    Vetoryl® Hard Capsules for Dogs 5mg
    SRP £2.20
    Save £0.83
  4. You save 37%
    Vetoryl Capsules 10mg 918
    Vetoryl® Capsules for Dogs 10mg
    SRP £2.29
    Save £0.87
  5. You save 34%
    Vetoryl Capsules 30mg 3101
    Vetoryl® Hard Capsules for Dogs 30mg
    SRP £2.83
    Save £0.99
View as Grid List

Showing 5 products

Set Descending Direction
per page

What Conditions Does Vetoryl Treat?

Vetoryl is a prescription-only medicine used to treat Cushing's disease in dogs. Cushing's disease is characterised by excessive cortisol production, a hormone that regulates metabolism, inflammation, and immune response.

What is Cushing's Disease in Dogs?

Cushing's disease in dogs, also known as hyperadrenocorticism, is a condition in which the body produces too much cortisol. Cortisol is a hormone produced by the adrenal glands. There are two primary types of Cushing's disease in dogs:

  1. 1. Pituitary-dependent Cushing's disease: This form is the most common, accounting for around 80-85% of cases. Caused by a non-cancerous tumour in the pituitary gland located at the base of the brain, the tumour stimulates the adrenal glands' overproduction of cortisol near the kidneys.
  2. 2. Adrenal-dependent Cushing's disease: In this less common form, a tumour develops within one or both adrenal glands, producing excessive cortisol. The tumour can be benign (non-cancerous) or, in rare cases, malignant (cancerous).

Cushing's disease can also occur in response to long-term administration of corticosteroid medications, such as prednisone, used to treat other conditions. This type is known as iatrogenic Cushing's syndrome.

How Does Vetoryl Work?

Vetoryl works by blocking the production of cortisol in the adrenal glands, helping to helps alleviate the symptoms associated with Cushing's disease, such as increased thirst and urination, weight gain, and hair loss.

Is Vetoryl Safe?

Vetoryl is safe for use in dogs when prescribed specifically by a vet and used as directed. However, it may cause some side effects, including: 

  • - Vomiting
  • - Diarrhoea
  • - Lethargy


However, these side effects are uncommon and generally reversible. If your pet experiences any side effects from Vetoryl, it's essential to contact your veterinarian immediately. Some side effects may be serious, and prompt veterinary attention is necessary.

How is Vetoryl Administered?

Vetoryl is usually administered orally once daily, with or without food. The dosage is determined based on the dog's weight. Vetoryl tablets are available as:

Only purchase the tablet sizes stated on the veterinary prescription and follow your vet’s advice regarding administration.  

How Long Does Vetoryl Take to Work?

The full effects of Vetoryl may take several weeks to become noticeable. However, most dogs will show some improvement within a few days of starting treatment.

Can Vetoryl be used with other medications?

 Vetoryl can be taken with other medications, but it's crucial to consult your veterinarian before administering additional medicines to your dog.

Can I get Vetoryl Without a Vet Prescription in the UK?

No, Vetoryl is a prescription-only medicine in the UK, meaning you cannot obtain it without a prescription from a veterinarian. For your pet's safety, always be wary of any organisation offering to sell any prescription-only veterinary medicines without a prescription.

Please note, while we have an onsite vet to oversee the supply of prescription medicines, we do not offer veterinary consultations or advice.