Vet prescription required in checkout

Frontline Spot On Combo X-Large Dog (40kg+)

You save 57%
Vet prescription required in checkout
You save 57%

Frontline Spot On Combo X-Large Dog (40kg+)

Frontline Spot On Combo for Dogs is for the treatment and prevention of flea and tick infestations and for the control of biting lice.
Standard Retail Price £48.24
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  • Details
  • Instructions
  • Delivery Info
  • Service Reviews (82049)

Frontline Spot On Combo X-Large Dog (40kg+)

Break the flea cycle - Frontline for Dogs kills fleas, ticks and lice. Frontline Combo prevents the multiplication of fleas by inhibiting the fleas eggs from developing.

Frontline Spot On Combo X-Large Dog is for the treatment and prevention of flea and tick infestations and for the control of biting lice.

It is supplied in packets of 3 or 6 single use pipettes.

This is a prescription item and will be sent once a valid prescription is received.


If you see the "prescription required" sign next to an item you’d like to order, it means the item can only be issued with a prescription. While you can add these items to your shopping cart and pay for them along with other non-prescription products, we can’t dispatch them until we’ve received a prescription.

Delivery Info

Please view our Delivery and Coronavirus pages for the latest updates.

Light (usually non-food) orders under £29 are charged £2.99 postage. Heavy (typically food) orders under £29 are charged £4.49 postage.

For Light items (under 2kg) our standard method is Royal Mail 2nd Class Tracked(there are a few exceptions, so if in doubt check our Delivery page).

To get it faster you can upgrade Light items to Royal Mail 1st Class Tracked or a Guaranteed Courier service, Saturday Courier or even before 12 noon services. There's a small fee, but if you're in a hurry they are worth considering. To ensure you get your courier order as quickly as possible, please place your order before 12 Noon Monday to Thursday. There is no standard Saturday courier delivery.

Heavy items weighing 2kg and more are sent via courier. Heavy items ordered after 12 Noon Friday, or anytime Saturday and Sunday will be processed on a normal working day.

Please note that if you are purchasing a mix of Light and Heavy items at the same time, these will be sent separately. The Heavy items being sent by Courier, the Light items by Royal Mail 2nd Class Tracked.

Refrigerated items are only dispatched by courier Monday to Thursday to ensure the item remains cool.

All exceptions to these guidelines are noted in the product description.

For more information, view our Delivery page.

Service Reviews (82049)
Independent Customer Feedback

Frontline Spot On Combo X-Large Dog (40kg+)

4.9/ 5
(82049 customer reviews)
  1. 5
    "Have used them for last 4 years and always provide excellent service .
    Fast delivery and excellent customer service when I spoke to them ."
    Review by / (Posted on
  2. 5
    "Ordering and uploading of prescriptions is so easy and efficient. The whole process of ordering and final delivery is excellent."
    Review by Bernard Griffiths / (Posted on
  3. 5
    "Very efficient service. Yes I would recommend them and I will be using them again."
    Review by Zoe Welland / (Posted on
  4. 5
    "sent out very quick very pleased with the service"
    Review by raymond obrien / (Posted on
  5. 5
    "Excellent service and easy ordering."
    Review by Lesley Bugler / (Posted on
  6. 5
    "So easy to get Bailey our dog, the eye ointment he needs at lower costs than the vet"
    Review by Linda Sparks / (Posted on
  7. 5
    "Easy to use and quick delivery."
    Review by Linda Mountford / (Posted on
  8. 5
    "Easy to place order, always prompt receipt emails, dispatch and updates.
    When had query on specific drug customer services helpful."
    Review by / (Posted on
  9. 5
    "Easy to use website, free delivery on most orders. Excellent delivery timescales and excellent delivery drivers. Good prices too."
    Review by / (Posted on
  10. 5
    "Their prices and quick delivery are brilliant, as are their choice of different products."
    Review by Linda Falconer / (Posted on
View all 82049 customer reviews

Vet prescription required in checkout

  1. Get a prescription from your vet
  2. Place your order with us
  3. Add a prescription and tell us about your pet.
  4. Our vets will double check your order & your order is dispatched right away
Learn more