Zylkene for Dogs and Cats

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SRP £0.00
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Zylkene is formulated to help your pet cope with changes in their environment or day to day life.

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The European Commission has recently issued a new regulation affecting Republic of Ireland and Northern Ireland preventing usage of E171 (an additive containing titanium dioxide) that will come into force in June 20, 2022. After reviewing the evidence, the UK Food Standards Agency (FSA) and Food Standards Scotland (FSS) did not identify any safety concerns and will not follow the European Union in banning titanium dioxide as a food additive at this time.  This additive is widely used in human pharmaceutical as well as animal nutrition products and has been for many years.

This new regulation affects our brand Zylkene® since E171 is present in the capsule ‘shell’, however E171 is not present in the powder.

In response to this new EC regulation, Vetoquinol have issued updated guidance to instruct pet owners to open the capsule and sprinkle the powder onto the food or on a treat. This clear guidance on how to administer Zylkene® should address any safety concern. 

Unfortunately, we are unable to continue supplying the  Zylkene® 20 pack to Northern Ireland customers until further notice as this packaging/labeling has not been changed.

Zylkene is a complementary feeding stuff for both cats and dogs; it contains a natural product, derived from casein, a protein in milk. It can be used for both dogs and cats to give owners the power to help their pets cope with different situations, such as the introduction of a new pet, new baby, house moves, multi-animal households, cattery or kennel stays, travelling, fireworks/loud noises, home alone or travel anxieties.

Zylkene for Dogs is available in 3 sizes, 75mg for small dogs, 225mg for medium sized dogs and 450mg for large dogs.  


It is available in
  • Cat & Small Dogs 75mg packs of 20 or 100 capsules.
  • Medium Dogs 225mg packs of 20 or 100 capsules.
  • Large Dogs 450mg packs of 20 or 100 capsules.

Key Benefits

  • Promotes pet relaxation.
  • Easy to give.
  • Non-Drowsy.
  • No side effects.


  • Cat & Small Dog 75mg
    Powder 77.3% - Casein (Trypsin hydrolysed bovine casein), Maltodextrin, Magnesium stearate Capsule 22.7% - Bovine skin gelatine.
  • Medium Dog 225mg
    Powder 76.9% - Casein (Trypsin hydrolysed bovine casein), Maltodextrin, Magnesium stearate Capsule 23.1% - Bovine skin gelatine​.
  • Large Dog 450mg
    Powder 82.9% - Casein (Trypsin hydrolysed bovine casein), Magnesium stearate Capsules 17.1% - Bovine skin gelatine

Zylkene is easy to give; once a day either directly into the mouth or by opening the capsule and mixing with food. For information on the size and quantity of tablets you should give your dog, see below. 


Dogs and cats weighing less than 5kg. 1 x 75mg capsule per day
Dogs and cats weighing 5-10kg. 2 x 75mg capsules per day
Dogs weighing 10-15kg. 1 x 225mg capsule per day
Dogs weighing 15-30kg. 2 x 225mg capsules per day OR 1 x 450mg capsule per day
Dogs weighing 30-60kg. 2 x 450mg capsules per day

What our vet says

What our vet says
"You can give your cat or dog Zylkene without prescription for times when they feel anxious for any reason. Pop the tablet in their mouth or mix with food when you feel they need it. It's a really effective calmer."
John Campbell - Head Veterinary Surgeon (BVM&S BSc MRCVS)
John Campbell Head Veterinary Surgeon And
Co-Founder (BVM&S BSc MRCVS)