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Advocate Spot On for Dogs 250 (10-25kg)
Simple steps for pet prescriptions
  • 1Get a prescription from your vet
  • 2Place your order with Pet Drugs Online
  • 3Attach a prescription and tell us about your pet, read more
  • 4Our vets will double check your order
  • 5Your order is dispatched right away
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Advocate Spot On for Dogs 250 (10-25kg)

This item requires a vet's prescription

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21336 Reviews

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  • Vet price £30.17
  • Our price £14.56
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Prescription Info.
Service Reviews

Advocate Spot On 250 (10-25kg)

Advocate Spot On is a treatment for fleas and their larvae, roundworm, hookworm, heartworm and ear mites in dogs.

It also treats lungworm, whipworm, biting lice, sarcoptes and demodex.

Advocate Spot On is supplied in packs of 3 or 6 single use pipettes.

This is a prescription item and will be sent once a valid prescription is received.

Full instructions for using Advocate Spot On included.

Click here to view the full range of Advocate Spot On for dogs

Advocate Spot On contains two active substances, imidacloprid and moxidectin.

Advocate comes in different strengths and pack sizes, depending on the size of the animal being treated. The medicine can only be obtained with a prescription. Advocate is applied from pre-filled pipettes. These are small plastic droppers, available in different sizes depending on the size of the animal, which are filled with the correct amount of Advocate for one treatment. The content of a full pipette is applied onto the animal’s skin, after parting the fur. Advocate for dogs is applied between the shoulder blades at the bottom of the dog’s head, but for large dogs (above 25 kg) the product should be applied in 3 or 4 spots along the dog’s back, whilst it is standing, from between its shoulder blades to the base of its tail.

The dose and frequency of application depends on why Advocate is being used; the package leaflet includes detailed information on dosage and duration of treatment.

Advocate Spot On is available to buy from Pet Drugs Online at up to 52% cheaper than your vet.

How does Advocate Spot On work?

Imidacloprid interferes with certain specific receptors (nicotinergic acetylcholine receptors) in the nervous systems of lice and fleas, which results in their subsequent paralysis and death.

Moxidectin causes paralysis and death of nematodes and heartworms by interfering with the way signals are passed between nerve cells (neurotransmission) in the parasites’ nervous system.

To check the most up to date information about this product, please read its Summary of Product Characteristics (SPC) on the Veterinary Medical Directorate’s (VMD) Product Information Database:

View summary of product characteristics (SPC)

We offer a range of delivery options:

Our standard delivery is free by Royal Mail 2nd Class - there are some exceptions and you can see these on our Delivery page. These include refridgerated items and aerosols which have to be sent via our Next Day Courier service.

We also offer delivery by Royal Mail 1st Class or a Next Day Courier service for a small fee (for items in stock ordered before 12pm Monday to Friday - excludes Saturday delivery).

Orders under £20 have a £2.50 handling fee automatically added.

Food deliveries weighing 2kg and over ordered before 12pm (Monday to Thursday) will be delivered next working day by courier - Monday to Friday - excludes Saturday delivery. Orders placed on a Friday, Saturday and Sunday will be delivered on a Tuesday. Orders weighing over 6kg are sent free.

For more information, view our Delivery and Returns page.

If you see the "prescription required" sign next to an item you’d like to order, it means the item can only be issued with a prescription. While you can add these items to your shopping cart and pay for them along with other non-prescription products, we can’t dispatch them until we’ve received a prescription.

Product reviews for prescription products are not allowed by the RCVS. But here is what our customers say about our service:

Service reviews have been compiled from 21334 customer reviews


happy with service


Easy to order and arrived in very good time


good service and great prices compared to rip off greedy vets..


Great fast service,


Esay to order and very quick delivery


Easy, smooth transaction.
I would definitely purchase from again.


good product ,well packaged & fast delivery .will shop again .thank you


Quick and easy to use . Low price and good value .


fantastic range of products, best prices and fast delivery.


Excellent service and prompt delivery as usual.


Wonderful service


Quick and easy experience even with a prescription. Delivery was fast and prices were so much lower than from the vet


great service all round... definately would recommend as a 1st user to the site. thank you for really speedy service..will be returning.


Fast delivery and low price.


Service was excellent no issues


You are always very friendly and efficient .


On a tight budget, so nice to afford the product my pet needs for his joints & feline cognitive decline.


Very quick and excellent service


Lots of good products. Great service


Excellent service answered all queries really quickly and delivery of order was swift. Will definitely order from here again.


The last two deliveries I have received have both arrived damaged - this one was packaged perfectly - very happy


Excellent service. Very quick delivery and excellent price.


Great quick service


Online service very good, easy to follow website. Confirmation of order and goods delivered promptly.


Easy wick no fuss

View all 21334 reviews