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Advocate Spot On for Dogs 250 (10-25kg)
Simple steps for pet prescriptions
  • 1Get a prescription from your vet
  • 2Place your order with Pet Drugs Online
  • 3Attach a prescription and tell us about your pet, read more
  • 4Our vets will double check your order
  • 5Your order is dispatched right away
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Advocate Spot On for Dogs 250 (10-25kg)

This item requires a vet's prescription

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22618 Reviews

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  • Save 52%
  • Vet price £30.17
  • Our price £14.56
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Prescription Info.
Service Reviews

Advocate Spot On 250 (10-25kg)

Advocate Spot On is a treatment for fleas and their larvae, roundworm, hookworm, heartworm and ear mites in dogs.

It also treats lungworm, whipworm, biting lice, sarcoptes and demodex.

Advocate Spot On is supplied in packs of 3 or 6 single use pipettes.

This is a prescription item and will be sent once a valid prescription is received.

Full instructions for using Advocate Spot On included.

Click here to view the full range of Advocate Spot On for dogs

Advocate Spot On contains two active substances, imidacloprid and moxidectin.

Advocate comes in different strengths and pack sizes, depending on the size of the animal being treated. The medicine can only be obtained with a prescription. Advocate is applied from pre-filled pipettes. These are small plastic droppers, available in different sizes depending on the size of the animal, which are filled with the correct amount of Advocate for one treatment. The content of a full pipette is applied onto the animal’s skin, after parting the fur. Advocate for dogs is applied between the shoulder blades at the bottom of the dog’s head, but for large dogs (above 25 kg) the product should be applied in 3 or 4 spots along the dog’s back, whilst it is standing, from between its shoulder blades to the base of its tail.

The dose and frequency of application depends on why Advocate is being used; the package leaflet includes detailed information on dosage and duration of treatment.

Advocate Spot On is available to buy from Pet Drugs Online at up to 52% cheaper than your vet.

How does Advocate Spot On work?

Imidacloprid interferes with certain specific receptors (nicotinergic acetylcholine receptors) in the nervous systems of lice and fleas, which results in their subsequent paralysis and death.

Moxidectin causes paralysis and death of nematodes and heartworms by interfering with the way signals are passed between nerve cells (neurotransmission) in the parasites’ nervous system.

To check the most up to date information about this product, please read its Summary of Product Characteristics (SPC) on the Veterinary Medical Directorate’s (VMD) Product Information Database:

View summary of product characteristics (SPC)

We offer a range of delivery options:

Our standard delivery is free by Royal Mail 2nd Class - there are some exceptions and you can see these on our Delivery page. These include refridgerated items and aerosols which have to be sent via our Next Day Courier service.

We also offer delivery by Royal Mail 1st Class or a Next Day Courier service for a small fee (for items in stock ordered before 12pm Monday to Friday - excludes Saturday delivery).

Orders under £20 have a £2.50 handling fee automatically added.

Food deliveries weighing 2kg and over ordered before 12pm (Monday to Thursday) will be delivered next working day by courier - Monday to Friday - excludes Saturday delivery. Orders placed on a Friday, Saturday and Sunday will be delivered on a Tuesday. Orders weighing over 6kg are sent free.

For more information, view our Delivery and Returns page.

If you see the "prescription required" sign next to an item you’d like to order, it means the item can only be issued with a prescription. While you can add these items to your shopping cart and pay for them along with other non-prescription products, we can’t dispatch them until we’ve received a prescription.

Product reviews for prescription products are not allowed by the RCVS. But here is what our customers say about our service:

Service reviews have been compiled from 22619 customer reviews


Greats service easy to do


Fast delivery!


Easy to use ordering and a competetive price with quick delivery.


Good service. Good product. Good price.


Speedy delivery. Dog happily eating product.


Good price . Dog yet to have these as still on expensive one from vet


Fantastic service quick delivery and excellent prices 5 stars


Very unhappy,have not received my product, email asking where it was got standard reply and no action, have not had purchase price refunded, still waiting.


Goid prices. Fast delivery


Excellent and very economical service provided


Excellent service, super speedy delivery, great prices.


Just as described. Quick post. Reliable


Excellenthe product, good price and fantastic speedy delivery.....hassle free.


Fast delivery never out of stock great customer service.


Very quick delivery


Quick delivery!!


Very easy process of ordering ordering online. Fast easy contact from company as one of the medicines unavailable at that time. Medicines arrived exactly as advised.


Continued good service and good prices, good selection of products


Excellent service and easy to use. Good value too, much cheaper than buying from vet.


Quick and easy, simple system to upload prescriptions and the tables turned up the next day


Brilliant service!


Fantastic well priced and fast shipping.


Delivered on time. Happy with product and much cheaper than buying at the vets.


Service excellent and web site very user friendly.


Easy to order. Good value. Items arrived very quickly. I have used this service many times.

View all 22619 reviews