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Advocate Spot On for Dogs 250 (10-25kg)
Simple steps for pet prescriptions
  • 1Get a prescription from your vet
  • 2Place your order with Pet Drugs Online
  • 3Attach a prescription and tell us about your pet, read more
  • 4Our vets will double check your order
  • 5Your order is dispatched right away
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Advocate Spot On for Dogs 250 (10-25kg)

This item requires a vet's prescription

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21164 Reviews

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  • Vet price £30.17
  • Our price £14.56
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Prescription Info.
Service Reviews

Advocate Spot On 250 (10-25kg)

Advocate Spot On is a treatment for fleas and their larvae, roundworm, hookworm, heartworm and ear mites in dogs.

It also treats lungworm, whipworm, biting lice, sarcoptes and demodex.

Advocate Spot On is supplied in packs of 3 or 6 single use pipettes.

This is a prescription item and will be sent once a valid prescription is received.

Full instructions for using Advocate Spot On included.

Click here to view the full range of Advocate Spot On for dogs

Advocate Spot On contains two active substances, imidacloprid and moxidectin.

Advocate comes in different strengths and pack sizes, depending on the size of the animal being treated. The medicine can only be obtained with a prescription. Advocate is applied from pre-filled pipettes. These are small plastic droppers, available in different sizes depending on the size of the animal, which are filled with the correct amount of Advocate for one treatment. The content of a full pipette is applied onto the animal’s skin, after parting the fur. Advocate for dogs is applied between the shoulder blades at the bottom of the dog’s head, but for large dogs (above 25 kg) the product should be applied in 3 or 4 spots along the dog’s back, whilst it is standing, from between its shoulder blades to the base of its tail.

The dose and frequency of application depends on why Advocate is being used; the package leaflet includes detailed information on dosage and duration of treatment.

Advocate Spot On is available to buy from Pet Drugs Online at up to 52% cheaper than your vet.

How does Advocate Spot On work?

Imidacloprid interferes with certain specific receptors (nicotinergic acetylcholine receptors) in the nervous systems of lice and fleas, which results in their subsequent paralysis and death.

Moxidectin causes paralysis and death of nematodes and heartworms by interfering with the way signals are passed between nerve cells (neurotransmission) in the parasites’ nervous system.

To check the most up to date information about this product, please read its Summary of Product Characteristics (SPC) on the Veterinary Medical Directorate’s (VMD) Product Information Database:

View summary of product characteristics (SPC)

We offer a range of delivery options:

Our standard delivery is free by Royal Mail 2nd Class - there are some exceptions and you can see these on our Delivery page. These include refridgerated items and aerosols which have to be sent via our Next Day Courier service.

We also offer delivery by Royal Mail 1st Class or a Next Day Courier service for a small fee (for items in stock ordered before 12pm Monday to Friday - excludes Saturday delivery).

Orders under £20 have a £2.50 handling fee automatically added.

Food deliveries weighing 2kg and over ordered before 12pm (Monday to Thursday) will be delivered next working day by courier - Monday to Friday - excludes Saturday delivery. Orders placed on a Friday, Saturday and Sunday will be delivered on a Tuesday. Orders weighing over 6kg are sent free.

For more information, view our Delivery and Returns page.

If you see the "prescription required" sign next to an item you’d like to order, it means the item can only be issued with a prescription. While you can add these items to your shopping cart and pay for them along with other non-prescription products, we can’t dispatch them until we’ve received a prescription.

Product reviews for prescription products are not allowed by the RCVS. But here is what our customers say about our service:

Service reviews have been compiled from 21168 customer reviews


fast and as described


Great customer service and far cheaper than vet's prices. A problem with my order (my mistake) was rectified quickly and efficiently. Just a shame I could only order 120 tablets when my prescription was for 100.


Their service is excellent: dog food always arrives the next day and this Burns food is the cheapest I have found.


The Web site was easy to use along with the registration process. Payment was straight forward. The European delivery options was why I used the company in the first place. The order was dispatched quickly and I was informed every step of the way and more to the point my order was delivered to my door in Spain with no problems.


Very fast and reliable and any queries you have are answered straight away.


Product ordered arrived in timescale I had been given


Good value, good service


Great service and great savings-my preferred online shop for all my dog's needs. Many thanks D


Excellent service once again. Thank you Sue B Chester


A good company to deal with, always my first port of call. Helpful if you need to ring. Used the different posting options all good even allowing for Royal Mail!!


Easy to order great product and great delivery thank you very much


Efficient service, quick delivery, knowledgeable supplier.


Good value and the goods I ordered arrived before date estimated


Quite good product (Evening primrose oil), I can see difference in my cat's fur in just couple of weeks. Will be coming back for more.


I have used them several times and have always been able to get what I require with out any problems. Delivery is reasonable and prices fantastic.




Good product description, good price and fast delivery


Good service and a good price for the products


Easy, stress free transaction and always a speedy delivery.


best price around


Quick service, website was easy to use.


Easy to place an order, no problem to upload my pet prescription. Quick delivery. Happy with the prices compared to other pet products on different websites, will order again from this company.


A very good service


Prompt delivery and helpful information about products. Cat took the medicine without any trouble.


As always a good service and fast delivery.

View all 21168 reviews