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Advocate Spot On for Dogs 400 ( > 25kg)
Simple steps for pet prescriptions
  • 1Get a prescription from your vet
  • 2Place your order with Pet Drugs Online
  • 3Attach a prescription and tell us about your pet, read more
  • 4Our vets will double check your order
  • 5Your order is dispatched right away
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Advocate Spot On for Dogs 400 ( > 25kg)

This item requires a vet's prescription

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30803 Reviews

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  • Vet price £37.00
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Estimated dispatch within 24 hours (subject to stock) See our delivery options

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Advocate Spot On for Extra Large Dogs 400 ( > 25kg)

Advocate Spot On is a treatment for fleas and their larvae, roundworm, hookworm, heartworm and ear mites in dogs.

It also treats lungworm, whipworm, biting lice, sarcoptes and demodex.

Advocate Spot On for Extra Large dogs is supplied in packs of 3 or 6 single use pipettes.

This is a prescription item and will be sent once a valid prescription is received.

Full instructions for using Advocate Spot On included.

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Looking for a different size?

Save over 50% on Advocate for Dogs and Cats by shopping with us:
View our full range of Advocate for dogs >
View our full range of Advocate for cats >

View our full range of spot on flea treatment for dogs >

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Advocate Spot On contains two active substances, imidacloprid and moxidectin.

Advocate comes in different strengths and pack sizes, depending on the size of the animal being treated. The medicine can only be obtained with a prescription. Advocate is applied from pre-filled pipettes. These are small plastic droppers, available in different sizes depending on the size of the animal, which are filled with the correct amount of Advocate for one treatment. The content of a full pipette is applied onto the animal’s skin, after parting the fur. Advocate for dogs is applied between the shoulder blades at the bottom of the dog’s head, but for large dogs (above 25 kg) the product should be applied in 3 or 4 spots along the dog’s back, whilst it is standing, from between its shoulder blades to the base of its tail.

The dose and frequency of application depends on why Advocate is being used; the package leaflet includes detailed information on dosage and duration of treatment.

Advocate Spot On is available to buy from Pet Drugs Online at up to 52% cheaper than your vet.

How does Advocate Spot On work?

Imidacloprid interferes with certain specific receptors (nicotinergic acetylcholine receptors) in the nervous systems of lice and fleas, which results in their subsequent paralysis and death.

Moxidectin causes paralysis and death of nematodes and heartworms by interfering with the way signals are passed between nerve cells (neurotransmission) in the parasites’ nervous system.

To check the most up to date information about this product, please read its Summary of Product Characteristics (SPC) on the Veterinary Medical Directorate’s (VMD) Product Information Database:

View summary of product characteristics (SPC)

We offer a range of delivery options:

Our standard delivery is free by Royal Mail 2nd Class (for lightweight items up to 2kg) - there are some exceptions and you can see these on our delivery page. These include refridgerated items, controlled prescription medication and heavy food items 2kg+ which have to be sent via our Courier service.

We also offer delivery by Royal Mail 1st Class or via Next Working Day Courier for a small fee (for items in stock ordered before 12pm Monday to Thursday). Where available orders can be upgraded to Next Working Day pre-12pm or Saturday Delivery. Standard courier orders placed before 12pm on Fridays will be delivered the following Monday.

Orders under £20 have a £2.50 handling fee automatically added.

Food deliveries weighing 2kg and over ordered before 12pm (Monday to Thursday) will be delivered next working day by courier - Monday to Friday - excludes Saturday delivery. Orders placed on a Friday, Saturday and Sunday will be delivered on a Tuesday. Orders weighing over 6kg are sent free.*

*Please note that any other items ordered with food will be sent separately via Royal Mail 2nd Class by default. If you require non-food items on a faster service we offer the option to upgrade to Royal Mail 1st Class or Courier delivery of non-food items for an additional charge.

For more information, view our delivery page.

If you see the "prescription required" sign next to an item you’d like to order, it means the item can only be issued with a prescription. While you can add these items to your shopping cart and pay for them along with other non-prescription products, we can’t dispatch them until we’ve received a prescription.

Product reviews for prescription products are not allowed by the RCVS. But here is what our customers say about our service:

Service reviews have been compiled from 30803 customer reviews

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Fab service

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Great prices prompt delivery you won’t find better they even answer the phone when you call what more do need

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Highly recommended and trusted pet supplier. Easy to use website, and easy to order online (especially repeat prescription drugs). Have looked after my dogs needs for many years now. Always prompt, always deliver on time and competitive prices.

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Good prices and prompt dispatch

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Fast and efficient service, wide range of products, reasonable prices.

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Excellent service, highly recommend ☺️

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Little confusing when order never came together but I got items in the end

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use them every time, superb service, excellent prices, what not to like,highly recommended

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I would highly recommend Pet Drugs Online and will definitely be using them again.Their service was excellent,from the ordering to the delivery but more importantly the price which was much cheaper than my vet charges.

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